Strong's 5299 (ὑπωπιάζω)

keep under, weary

to hit under the eye (buffet or disable an antagonist as a pugilist), i.e. (figuratively) to tease or annoy (into compliance), subdue (one's passions)

from a compound of G5259 (ὑπό) and a derivative of G3700 (ὀπτάνομαι);